5 CLINICAL NEUROSCIENCES UPDATE SUMMER 2018 Current CSC researchers and their studies include: • John Cole, MD, MS, Associate Professor of Neurology, studies the genetic mechanisms that predispose patients to having strokes in order to prevent them. He currently is working with an American Heart Association Grant, augmented by a grant by Bayer Pharmaceutical, to study small vessel stroke genetics. Dr. Cole and his team maintain a Stroke Biorepository, which banks genetics samples and stroke outcome data. • Carolyn Cronin, MD, PhD, Assistant Professor of Neurology, is the local site primary investigator for StrokeNet, a network of 25 regional centers, involving 200 hospitals, that is dedicated to the conduct of stroke trials. Dr. Cronin was the site primary investigator for the POINT trial, a pivotal trial for patients with TIA or low National Institutes of Stroke Scale Scores. Currently, she is the primary investigator for the CHARM Study: Glibenclamide for large hemispheric infarction analyzing mRS and mortality. The primary purpose of this study is to determine if the study drug decreases malignant edema in large ischemic stroke. • Steven Kittner, MD, MPH, Professor of Neurology, leads an international consortium working together to understand the genetic determinants of early-onset ischemic stroke, an age group where genetic factors are particularly important. He also collaborates with a multi- site study aiming to understand the genetic underpinnings of intracerebral hemorrhage and the factors predicting outcome of this devastating type of stroke. • Michael Phipps, MD, MHS works as an advisor to Chesapeake Regional Information System for our Patients (CRISP), a regional health information exchange (HIE) serving Maryland and the District of Columbia. His specific interest is employing the online CRISP portal to share “emergent imaging,” where critical stroke patient images are automatically uploaded into the cloud for quick access. Because data-heavy images like CT angiograms can take some time to upload, this preemptive step will save valuable time in remote diagnostic review and treatment decisions. Dr. Phipps also is leading the effort in creating a Telestroke video-conferencing system, where CSC faculty can discuss patient cases with remote physicians in real time. • Karen Yarbrough, DNP, CRNP is SCS’s Programs Director and serves as chairperson of the Maryland Stroke Center Consortium, which facilitates policy development to remove disparities for acute stroke care due to geography, race, culture, socioeconomic status, gender and other barriers that impede the rapid triage of the stroke patient. n The University of Maryland Comprehensive Stroke Center – Faculty & Staff Neurology • John Walden Cole, MD, MS Associate Professor of Neurology • Carolyn Cronin, MD, PhD Assistant Professor of Neurology • Tara L. M. Dutta, MD Assistant Professor of Neurology • Steven J. Kittner, MD, MPH Professor of Neurology • Jose Merino-Juarez, MD, MPhil Associate Professor of Neurology • Melissa Motta, MD Assistant Professor of Neurology and Program in Trauma • Michael Phipps, MD, MHS Assistant Professor of Neurology • Marcella Wozniak, MD, PhD Associate Professor of Neurology Neurosurgery • E. Francois Aldrich, MD Professor of Neurosurgery • Elizabeth J. Le, MD Assistant Professor of Neurosurgery • J Marc Simard, MD, PhD Professor of Neurosurgery Interventional Neuroradiology • Dheeraj Gandhi, MBBS Professor of Diagnostic Radiology • Gaurav Jindal, MD Assistant Professor of Diagnostic Radiology • Timothy Miller, MD Assistant Professor of Diagnostic Radiology • Elizabeth J. Le, MD Assistant Professor of Neurosurgery Stroke Rehabilitation • Peter H. Gorman, MD Associate Professor of Neurology • Glenn Joseph Kehs, MD Assistant Professor of Neurology • Robynne Melissa Braun, MD Assistant Professor of Neurology Vascular Surgery • Rajabrata Sarkar, MD, PhD Professor of Surgery • Brajesh Kumar Lal, MD Professor of Surgery Staff • Karen L. Yarbrough, DNP, CRNP, ACNP-BC Clinical Director, UMMC Comprehensive Stroke Center • Chad Schrier, BSN, RN, CEN Stroke Coordinator