b'INNOVATION IN MOTIONcontinuedgeneration of movement disorderpostures. The DynaPort capturesa large number of the dopamine experts is a priority. Over the years,in minute detail, performance ofproducing neurons in the brain have we have trained many fellows whogait and balance. In the long term,already been injured, she says. have gone into practice in locationsHowever, if we were able to detect where previously, there was nothe onset of these brain changes specialty care available for movementearlier, we could act proactively, to disorder patients, Dr. Shulmanforestall or even stop the diseases notes. Our graduating fellows haveprogression.established movement disorderIn another research study, Dr. Fishman practices in Western Maryland,is a co-investigator with principal Annapolis and the state of Delawareinvestigator Howard M. Eisenberg, (see page 8). This year, one of ourMD, Professor of Neurosurgery at graduates began the first movementUMSOM, in a phase 3 study to test disorder neurology practice in thethe safety and efficacy of using entire state of Montana! MRI-guided focused ultrasound Notably, all of the CentersThe Dynaport triaxial accelerometer captureson the brain to treat Parkinsons neurologists are actively involved inevery aspect of a patients mobility and balance disease. The pivotal study is the final research and clinical trials designedwe hope to identifyso-calledstep before the U.S. Food and Drug to reduce or delay the effects of PDmovement signatures or profilesAdministration (FDA) will consider and other movement disorders. Wethat correspond to specific types ofapproving this new technology for strive to provide clinical researchsymptoms or diagnoses, says Dr.widespread use as a nonsurgical opportunities so that patientsShulman. We speculate that thetreatment option to alleviate the key can participate in expanding theextreme sensitivity of a sensor likemotor symptoms of this common knowledge in these fields, says this will be able to detect changesneurological condition. The two Dr. Shulman.in movement associated with earlyphysicians have collaborated closely In one such study, Dr. ShulmanParkinsons disease even beforefor a number of years and were is collaborating with Rainer vonthe experienced neurologists eyesinstrumental in the success of a Coelln, Dr Med, Assistant Professorcan perceive it. She points out thatcollaborative study that showed of Neurology, to improve the testinghaving such a diagnostic tool couldthat MRI-guided focused ultrasound of patient mobility by using abe a huge breakthrough. Detectingcan effectively treat patients with wearable sensor device, the DynaPortthe diagnosis of neurodegenerativeessential tremor (ET). This work ledtriaxial accelerometer. This highlydisorders like Parkinsons diseaseto the 2016 approval of this treatment sensitive motion detector is wornearlier is the holy grail of our field.by the FDA.by a patient while performing a setFor example, in Parkinsons disease, number of walks, turns, and standingwhen PD symptoms become obvious, FACULTY & STAFFMovement Disorders Faculty: Lisa M. Shulman, MDResearch Staff:Paul S. Fishman, MD, PhDProfessor of NeurologyKimberly Bambarger Professor of NeurologyEugenia Brin Professor in Parkinsons DiseaseVeronica Fallon Chief, Neurology Service, Maryland VA and Movement DisordersPhilip HeiserHealth Care System The Rosalyn Newman Distinguished Scholarin Parkinsons DiseaseNurse:Stephen G. Reich, MDDirector, University of Maryland ParkinsonsSharon PowelFrederick Henry Prince Distinguished Disease and Movement Disorders CenterProfessor in Neurology Administrative Staff:Friedrich Rainer von Coelln, Dr MedCherika Jones Joseph M. Savitt, MD, PhDAssistant Professor of Neurology Erica MilesAssociate Professor of NeurologyMovement Disorders Staff:Clinical Division Manager: Christina Griffin4 CLINICAL NEUROSCIENCES UPDATEFALL 2019'