It is our sincere pleasure to present our second “Clinical Neurosciences Update” from the Departments of Neurology and Neurosurgery. The current issue focuses on vascular neurosciences and in particular the approach and care of patients with acute ischemic or hemorrhagic stroke. Our nationally designated Comprehensive Stroke Center (CSC) is among the busiest in the Mid-Atlantic region and provides high acuity, emergent care. The CSC is a highly collaborative and interdisciplinary team that includes neurology, neurosurgery, interventional neuroradiology, and emergency medicine to perform complicated and often life-saving procedures such as thrombolysis and thrombectomy. In this issue, we highlight Dr. Marc Simard, a clinician-scientist, vascular neurosurgeon, who has pioneered experimental approaches to the treatment of increased intracranial pressure, brain swelling, and sub-arachnoid hemorrhage. The close collaboration between Neurology and Neurosurgery for patient care and research helps us to lead the region in many areas of clinical neuroscience such as stroke, epilepsy, and movement disorders, supported by such advanced services as the Neurocritical Care and Emergency Neurology Unit, which is specially equipped to care for the sickest patients when timely care is critical. We continue to strive daily for the best patient outcomes and to embrace new technologies and treatments that will insure the health of our patients. Clinical neurosciences here at University of Maryland Medical Center and University of Maryland School of Medicine continue to grow with enhanced research funding, new clinical trials, expanded patient outreach, and ongoing national reputation for excellence. It remains our privilege to serve our patient communities. Howard M. Eisenberg, MD R.K. Thompson Professor and Chair of the Department of Neurology Peter B. Crino, MD, PhD Professor and Chair Department of Neurology LETTER FROM THE CHAIRS ON THE COVER Comprehensive Stroke Center team members (L to R) Dheeraj Gandhi, MBBS; Carolyn Cronin, MD, PhD; Michael Phipps, MD, MHS; Marcella Wozniak, MD, PhD; and Steven J. Kittner, MD, MPH. Howard M. Eisenberg, MD Peter B. Crino, MD, PhD