b'childhood fractures can have long- common kind of skeletal tumorInjury, which was supported by the term consequences. This type ofduring childhood or adolescence, skeletal imbalance problem is verybrings in Dr. Masahiro Iwamoto common in orthopaedics, he says.and Dr. Vincent Y. Ng, Assistant Surgeries are invasive and recoveryProfessor of Orthopaedics and a painful. I thought, Can we replacespecialist in orthopaedic oncology this invasive surgery with drugand surgery as Co-Investigators,Collaboration is a great treatment? and Dr. Abzug and Dr. Herzenberg The number of funded researchas active collaborators. Thestrength of Orthopaedics, projects currently underway withIwamotos extend the studies onallowing us to extend our the Iwamotos serving as Principalretinoids to the pharmacologicalresearch in new directions. Investigators underscores thetherapy for chondrosarcoma withThis is the reason why extent to which others support theirDr. Ng, who received a 2020 - 2021we decided to join the line of inquiry. Recent grants fromAccelerated Translational Incubator the National Institutes of HealthsPilot (ATIP) Grant from theDepartment. National Institute of Arthritis andUniversity of Maryland, Baltimore Masahiro Iwamoto, MDMusculoskeletal and Skin Diseases,(UMB) Institute for Clinical and the US Department of Defense,Translational Research (ICTR) for and the American Foundation forthis project.Surgery of the Hand reflect growingIn addition, Dr. Enomoto-Iwamotorecognition of the work of theis combining her unique expertise American Foundation for Surgery Iwamotos in collaboration with theirin cellular signaling mechanismsof the Hand.clinical faculty partners and theirwith those of UMSOM handCollaboration is a great strength of critical contributions in bringingsurgeon Ngozi M. Akabudike,Orthopaedics, allowing us to extend novel ideas to fruition. MD, Assistant Professor ofour research in new directions, Orthopaedics, in a study entitledsays Dr. Mashiro Iwamoto. This is THE BENEFITS OFReprogramming of Metabolismthe reason why we decided to join COLLABORATION in Human Tendon Progenitors atthe Department.We have been collaborating and consulting clinicians with various specialties, explains Dr. Masahiro Iwamoto. For example, on a recent NIH grant project, Joshua M. Abzug, MD, Associate Professor of Orthopaedics and Pediatrics, serves as Co-Investigator, along with John Herzenberg, MD, Volunteer Clinical Professor of Orthopaedics, as a consultant for the project. Working together, he explains, we obtain human surgical specimens and study a variety of growth-plate pathologies and retinoid signaling in human cartilage.Dr. Motomi Enomoto-Iwamotos work also embraces collaboration with other UMSOM orthopaedic experts. Her NIH grant to study osteochondroma, the mostDr. Motomi Enomoto-Iwamotos research centers currently on osteochondroma, the most common kind of skeletal tumor during childhood.Department of Orthopaedics 2019Annual Report13'